ColoClear has a higher sensitivity rate when compared to other faecal DNA tests that are approved for clinical use [source].
A colonoscopy is still considered to be the gold standard to diagnose colorectal cancer, therefore ColoClear is not a replacement for a colonoscopy. ColoClear's test results should be interpreted as such:
- A “Negative” test result indicates a low probability of having colorectal cancer and/or advanced adenomas, however it does not guarantee the absence of colorectal cancer and/or advanced adenomas.
- A “Positive” test result indicates a high probability for the presence of colorectal cancer, advanced adenomas or benign neoplasia, but does not guarantee the presence of these conditions when a colonoscopy is performed as a follow-up procedure.
Aside from the gold-standard colonoscopy, there are other stool-based colorectal cancer screening tests available in the market, such as the faecal immunochemical test. You can compare the testing method and procedure in the diagram below: